Aortic stenosis is a narrowing of the aortic valve that affects how blood flows through the heart and body. While not often linked to heart valve narrowing, high and irregular blood pressure can ...
The aortic valve allows blood to leave the heart and travel through the aorta, which is the largest artery in the body. Aortic stenosis is when this heart valve narrows and doesn’t open fully. The ...
Mechanisms of heart-valve disease often mimic processes observed in embryonic and early childhood development, including activation of valvular interstitial cell (VIC) phenotypes and remodeling of ...