In this study, the duration of enzyme induction provoked by unlabelled lactose ureide (LU) in orocaecal transit time (OCTT) measurements with lactose-[13 C]ureide (13 C-LU) was evaluated. Without ...

A white female infant had first been noted to be jaundiced shortly after birth. She was the product of an uncomplicated pregnancy in a 21-year-old gravida 3, para 2. The birth weight was 3.45 kg.

Drugs are metabolized in the liver using several enzyme-catalyzed processes. These enzymes are collectively referred to as the hepatic microsomal enzyme system, and they are usually present in the ...

HIGHER animals may change in their response to drugs because of a decrease in the sensitivity of drug receptor sites in the organism, or because of accelerated drug metabolism. The latter has been ...

The dietary induction of serine dehydrase, produced by the oral intubation of hydrolyzed casein to protein-depleted rats, is markedly inhibited by doses of γ-radiation of 400 roentgens or higher ...

Phase I study of AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases: A pharmacokinetic (PK)-pharmacodynamic (PD) study to identify the optimal therapeutic dose ...

The interaction between Botrytis cinerea Pers. and grapevine (Vitis vinifera L.) was studied in a model system of reduced complexity. Cultured plant cells and fragments of fungal cell wall were used ...