The field of cancer epigenetics examines how heritable changes in gene regulation - independent of DNA sequence - impact ...

The role of epigenetic mechanisms in cancer has gained interest in recent studies. The reversible nature of epigenetic changes on genomic DNA and histones holds promise for the development of ...

The path a cell takes from healthy to metastatic cancer is mostly driven by epigenetic changes, according to a new computational study. The path a cell takes from healthy to metastatic cancer is ...

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a new study. The preclinical research ...

Background PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...

This review is designed by Dr. Yinglan Zhao and written by her PhD students Dr. Lei Tao and Yue Zhou (Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University).

DNA mutations in oncogenes and tumor suppressor genes drive tumorigenesis, but epigenetic modifications, such as DNA methylation, take center stage in a new era of cancer research. 1 In a study ...

Epigenetics is an emerging field of scientific research exploring the study of gene expression changes that occur without alterations to the DNA sequence itself. Image Credit: Juan ...

The role of epigenetic mechanisms, such as DNA or RNA methylation, histone modifications, nucleosome changes, and non-coding RNAs in cancer has gained increasing interest in recent studies. The ...

A new preclinical study by Van Andel Institute Professor Dr. Scott Rothbart and colleagues reveals how two epigenetic cancer medications approved for separate uses may hold promise for treating ...