Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

The field of cancer epigenetics examines how heritable changes in gene regulation - independent of DNA sequence - impact ...

Recent advancements include targeted agents, immunotherapy, and fertility-sparing surgeries for patients with advanced ...

Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes. The new research shows that if epigenetics ...

In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes ...

Cervical cancer rates are on the rise among younger women, owing in part to a lack of awareness, screening and prevention. A new study found that the percentage of women screened for cervical cancer ...