Based on the novel scaffold generated by Chemistry42, ISM6331 is a highly novel molecule with best-in-class potential. Being a pan-TEAD inhibitor, ISM6331 has shown potent efficacy at a low dose, as ...
The structure of a potent and selective TYK2 inhibitor, NDI-034858 (NTX-973), which was found clinically effective in autoimmune and inflammatory diseases, was disclosed for the first time by ...