August 20, 2009 (Cambridge, United Kingdom) — Coronary heart disease (CHD) risk is not associated with the APOE genotype after cardiovascular risk factors are controlled for, particularly the ratio of ...

Cambridge, UK - A large analysis has shown there is an approximately linear relationship between various apolipoprotein E (apoE) genotypes with LDL-cholesterol levels and coronary heart disease risk ...

For each parameter measured, or calculated from measurements, the values for individual animals were averaged per experimental group, and the SD of the group mean was calculated. The statistical ...

The APOE gene exacerbates pathology not only of the amyloid variety, but tau, as well. Previous research has tied ApoE’s effect on tau to microglial activation, but how does ApoE trigger microglia? In ...

We enrolled 13 patients with LPG from 9 unrelated Japanese families who were diagnosed by renal biopsy from age 7 to 79 years. Some of them were previously reported. After informed consent was ...

ST. LOUIS, Dec. 7, 2011 /PRNewswire/ -- Sigma-Aldrich® Corporation (Nasdaq: SIAL) today announced that Sigma Advanced Genetic Engineering (SAGE™) Labs, an initiative of Sigma Life Science, has made ...

Well known in the cardiovascular field for keeping blood cholesterol at bay, low-density lipoprotein receptors (LDLRs) seem to do the same in Alzheimer disease by helping to remove amyloid-β peptides ...

Researchers with the Atlanta Veterans Affairs Medical Center and Emory University have found a link between high LDL cholesterol levels and early-onset Alzheimer's disease. The results could help ...

Researchers found a link between high LDL cholesterol and early-onset Alzheimer's disease. The results could help doctors understand how the disease develops and what the possible causes are, ...