Multivalent interactions between biological molecules result in the formation of biomolecular condensates, a phenomenon known as Liquid–liquid phase separation (LLPS). Biomolecular condensates have ...

Since the first observations that many cellular compartments are formed via protein liquid-liquid phase separation (LLPS), the field studying this phenomenon grew exponentially, enriching literature ...

Scientists elucidated characteristics of PAS through observing the Atg protein using a fluorescence microscope and successfully reconstituted PAS in vitro. The team revealed, for the first time, that ...

The separation process can be conducted using various instruments, but the most fitting method depends on the mixture’s properties. This article covers the importance of solid-liquid separation in the ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...