GEN

Mechanistic Modeling for rAAV Enrichment

Increasing scrutiny and an evolving understanding of the impact of capsid impurities in recombinant adeno-associated virus (rAAV)-based therapies has catalyzed efforts to eliminate them from ...
MIT Technology Review

Mechanistic interpretability

But last year we got the best sense yet of how LLMs function, as researchers at top AI companies began developing new ways to ...
Nasdaq

FDA grants Simulations Plus to use PBPK to expand mechanistic modeling for LAI

Simulations Plus (SLP) announced that it has been awarded a newly funded grant from the U.S. Food and Drug Administration FDA to use physiologically based pharmacokinetic PBPK approaches in GastroPlus ...
GEN

Connected Downstream Models for Accurate Process Predictions

Models of biopharmaceutical production processes are more accurate and predictive if all downstream steps are considered together rather than individually. At least that’s according to researchers at ...
Business Wire

Simulations Plus and the University of Connecticut Receive New FDA Grant to Expand Mechanistic Modeling Approaches for Long-Acting Injectables

LANCASTER, Calif.--(BUSINESS WIRE)--Simulations Plus, Inc. (Nasdaq: SLP) (“Simulations Plus”), a leading provider of biosimulation, simulation-enabled performance and intelligence solutions, and ...
Pharmabiz

Applied BioMath collaborates with Revitope for mechanistic PK/PD modeling in solid tumors

Applied BioMath, the industry-leader in applying mechanistic modeling, simulation, and analysis to de-risk and accelerate drug research and development, announced a collaboration with Revitope for an ...
Fast Company

Anthropic takes a look into the ‘black box’ of AI models

Progress in mechanistic interpretability could lead to major advances in making large AI models safe and bias-free. The Anthropic researchers, in other words, wanted to learn about the higher-order ...