Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Researchers have solved a mystery about the most important driver of cancer development - a mutant protein found in half of all cancers - and how it contributes to tumor growth. Researchers from WEHI ...

A new study has, for the first time, settled the debate about how a mutated protein present in half of all human cancers drives tumor growth. The discovery will not only facilitate a rethink of the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

In many neurodegenerative disorders, abnormal proteins progressively aggregate and propagate in the brain. But what comes first, aggregation or propagation? Researchers from Japan share some new ...

Researchers from Tokyo Medical and Dental University (TMDU) show that the protein involved in Parkinson’s disease, α-synuclein, can propagate through the lymphatic system of the brain before it ...