This is a preview. Log in through your library . Abstract The history of the relationship of biological activity to partition coefficient and related properties is briefly reviewed. The dominance of ...

BMC Clin Pharmacol. 2010;10:1-27. It is assumed that the tissue consists of N capillaries/cm 3, all with exactly the same geometry, blood flow, permeability, etc. It is also assumed that the relation ...

The ratio that indicates whether an element is more soluble in liquid iron or molten silicate is called the partition coefficient. This figure shows that nitrogen has a greater affinity for liquid ...

BMC Clin Pharmacol. 2010;10:1-27. One can use this value of PS to estimate the "equivalent" thickness of the rat blood-adipose diffusion limiting barrier. The permeability is equal to: where D W is ...