Like a poison pen, dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues in the UConn School of Medicine report in the Jan. 23 issue of Cell.

Severe bacterial infections can push the human body into sepsis, a life-threatening cascade of inflammation and cell death that can be difficult to cure. Scientists and doctors have long puzzled over ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Opsonix, Inc. today announced the company’s launch with an $8 million Series A financing to develop a pathogen-extracting therapy designed to remove infectious ...

“We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe ...

Sepsis is a complex, serious condition that affects more than 400,000 people in the US each year. It begins when a bacterial infection produces endotoxins called lipopolysaccharides that bind to ...

A new venture launched by Harvard University, Opsonix Inc., is developing an external device that cleans the blood of patients with sepsis in a process akin to dialysis treatment. The device comes ...

Numerous previous attempts to develop therapeutic treatments, directed at discreet targets of the sepsis cascade, could not cope with the complex pathophysiology of sepsis and failed. Studies in a ...