Engineering retroviruses into vectors of therapeutic value has been a highly pursued effort. To date, the promise of retroviral-mediated gene delivery to treat or even cure genetic diseases has been ...
Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource
Research in gene therapy involving genome-integrating vectors now often includes analysis of vector integration sites across the genome using methods such as ligation-mediated PCR (LM-PCR) or linear ...
The location of integration of a gene therapy has been crucial for the safety and efficacy of the treatment to cure infants with X-linked severe combined immunodeficiency. Identified integrome ...
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