This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...

In addition to ALS, pridopidine is in late-stage clinical development for HD, with Prilenia and Ferrer planning to initiate a confirmatory study in HD designed to confirm pridopidine's effects and ...

Through a recent notice, the Undergraduate Medical Education Board (UGMEB) of the National Medical Commission (NMC) has ...

Anavex had proposed restricting the drug's indication to patients with early Alzheimer's without mutations in the SIGMAR1 gene.

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

Scott Nevil is an experienced writer and editor with a demonstrated history of publishing content for Investopedia. He goes in-depth to create informative and actionable content around monetary policy ...

Background Chronic pancreatitis (CP) is a risk factor for pancreatic cancer, with inherited cases conferring a markedly increased risk. The underlying mechanisms driving malignant transformation by CP ...

This paper presents an important advance in genetically encoded voltage imaging of the developing zebrafish spinal cord in vivo, capturing voltage dynamics in neuronal populations, single cells, and ...

Lymphocyte activation occurs when lymphocytes (B cells or T cells) are triggered through antigen-specific receptors on their cell surface. This causes the cells to proliferate and differentiate into ...

FDA clearance received to start the pivotal, 500-patient, placebo-controlled Phase 3 "PREVAiLS" study of pridopidine in participants with early, rapidly progressive ALS; US recruitment set to begin ...

Swiss Re AG ( OTCPK:SSREY) Discusses Strategic Outlook and Mindset for Achieving Market Leadership December 5, 2025 5:00 AM EST Good morning from the Swiss Re offices here in London, at the Gherkin.