Americans are drinking less than they have in decades. But a new study on mice shows even one bottomless brunch may shrink the small intestine’s nutrient-absorbing surface and spark inflammation that ...

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts.

Neural crest cells are a population of stem cells that invade the embryo in early development. They play a big role in what ...

A human intestinal organoid, displaying typical ‘budding crypts’ and a central ‘villus-like’ domain. The main intestinal cell types are shown in green, blue, red and purple. Membranes are yellow and ...

The esophagus, small intestine, and large intestine arise from a common early gut tube and adopt unique morphologies, but how the embryo differentially shapes gastrointestinal subregions has remained ...

This story is part of a series exploring human anatomy and physiology complexities. Each story in this collection showcases discoveries reshaping our understanding of the body's inner workings, ...

Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Hubei Key Laboratory of Drug Target Research and ...