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  1. Acetaminophen Overdose and NAC Dosing - MDCalc

    The Acetaminophen Overdose and NAC dosing Calculates PO or IV dosing of N-acetylcysteine (NAC) for acetaminophen overdose.

  2. Protocol NAC-IV | Poison Control | University of Utah Health

    Aug 23, 2025 · Antihistamines may be given, but usually no treatment is required. If given according to protocol, diluted to a 3% solution, and infused slowly over an hour, the incidence …

  3. IV NAC Protocol - Poison Alerts - Missouri Poison Center

    Jun 12, 2017 · These protocols may offer acceptable alternatives to the three-bag FDA-approved regimen. Despite which regimen is selected, hospitals should choose one to be used across …

  4. Acetaminophen toxicity - EMCrit Project

    Aug 28, 2025 · N-acetylcysteine can be used in patients with a history of anaphylactoid reactions (although it may be wise to initiate the infusion at a lower dose and pre-treat with antihistamines).

  5. N-acetylcysteine • LITFL Medical Blog • Toxicology Library …

    Nov 3, 2020 · N-acetylcysteine (NAC) is the most widely used sulfhydryl donor in the treatment of paracetamol poisoning. Standard therapy consists of a series of three infusions given over 20 …

  6. Recently, this center developed new recommendations for intravenous N-acetylcysteine (IV NAC) dosing. Previously on a case-by-case basis, the WPC recommended that selected patients at …

  7. NHSGGC Adult Paracetamol Overdose Protocol and Shortened N-acetylcysteine (NAC) Administration Chart A guideline is intended to assist healthcare professionals in the choice of …

  8. Acetylcysteine (NAC) is given to prevent liver damage after paracetamol overdose. The standard regimen for NAC treatment is 21-hours. The Scottish and Newcastle Anti-emetic Pre-treatment …

  9. For those patients who have taken a potentially toxic amount of acetaminophen, intravenous N-Acetylcysteine is the recommended treatment. Using a 3% solution, the following dosing …

  10. Nov 2, 2004 · The California Poison Control System (CPCS) recognizes that there are several approaches to treating acute acetaminophen poisonings ranging from 20 hour IV NAC to 72 …