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Structural Chromosome Aberrations: Translocations, Inversions, and Insertions
Structural chromosome abnormalities arise from **breaks in DNA** that can occur at any point, though they are most common at specific **recombination or fragile hotspots**. These disruptions lead to **intrachromosomal changes**, such as inversions and insertions within a single chromosome, or **interchromosomal translocations** between ...
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